Food diet uric acid
Uric acid is a heterocyclic compound of carbon, nitrogen, oxygen, and hydrogen with the formula C 5 H 4 N 4 O 3. This low solubility is significant for the etiology of gout. The solubility of the acid and its salts in ethanol is very low or negligible. It is aromatic because of the purine functional group. All these salts exhibit greater solubility in hot water than cold, allowing for easy recrystallization. Uric acid is a product of the metabolic breakdown of purine nucleotides, and it is a normal component of urine. Solubility of urate salts (grams of water per gram of compound). High blood concentrations of uric acid can lead to gout and are associated with other medical conditions including diabetes and the formation of ammonium acid urate kidney stones. It forms ions and salts known as urates and acid urates, such as ammonium acid urate. The five-membered ring also possesses a keto group (in the 8 position), flanked by two secondary amino groups (in the 7 and 9 positions), and deprotonation of one of these at high pH could explain the p K 2 and behavior as a diprotic acid.
In birds and reptiles, and in some desert dwelling mammals (e. In humans and higher primates, uric acid is the final oxidation (breakdown) product of purine metabolism and is excreted in urine. Similar tautomeric rearrangement and pi-resonance stabilization would then give the ion some degree of stability. Completing the CAPTCHA proves you are a human and gives you temporary access to the web property. If you are at an office or shared network, you can ask the network administrator to run a scan across the network looking for misconfigured or infected devices. If you are on a personal connection, like at home, you can run an anti-virus scan on your device to make sure it is not infected with malware. The figures given indicate what mass of water is required to dissolve a unit mass of compound indicated. In general, the water solubility of uric acid and its alkali metal and alkaline earth salts is rather low. The enzyme xanthine oxidase catalyzes formation of uric acid from xanthine and hypoxanthine, which in turn are produced from other purines. As its second ionization is so weak, the full urate salts tend to hydrolyze back to hydrogen urate salts and free base at pH values around neutral.
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Food diet uric acid
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